Jagdish Rai Dudhwal

Sem3: HGC

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syllabus of HGC only

UNIT-I
1. Mendelian Inheritance
any text book
 Mendelian inheritance
2. The concept of Genetics polymorphism
concept of polymorphism
DNA profiling
3. Blood groups: ABO, MN and Rh systems, ABH saliva secretion
Forensic Biology by Richard Li: pp.153-173
 MNS antigen system
 ABO Typing Techniques  
4. Haemoglobin
Hemoglobin
Hemoglobin D-Punjab
Confirmatory Tests blood 
5. Serum Proteins: Hptoglobin
 Serum Protein Polymorphisms
 
Haptoglobin
6. Inborn errors of metabolism: Albinism, Phenylketonuria and Alkaptonuria PTC

Albinism
Alkaptonuria
Phenylketonuria
Phenylthiocarbamide
PTC: Genes and Bitter Taste
7. taste sensitivity and Glucose
 https://en.wikipedia.org/wiki/Sweetness
8. Hardy-Weinberg Law,
The Hardy-Weinberg Law
The Hardy-Weinberg law 2
9. Mutations and Genetic Drift,
 http://learn.genetics.utah.edu/content/variation/mutation/
Genetic drift
10. Evolution Molecular basis of Evolution
Molecular Clocks

11. Natural Selection, Mutation, 
Evolutionary Genetics
12. Genetic Segregation
Genetic Drift

13. Genetic Distance
IAM based distance measures
Mutation, Migration, and Genetic Drift 
14. Effects of Migration, Marriages and Consanguinity,
Mutation
Consanguinity

UNIT-II
1. General introduction Human Cytogenetics, Nomenclature Standardization in Human Cytogenetics
 Chromosomes and Cytogenetics
2. Mitosis Meiosis in Males meiosis in Females
 and http://www.nature.com/scitable/topicpage/mitosis-and-cell-division-205
and any text book  
3. Chromosome structure and cell division
http://www.nature.com/scitable/topicpage/chromosomes-14121320
http://www.nature.com/scitable/topicpage/chromosome-mapping-idiograms-302

4. Human somatic chromosomes, Morphological variability of human chromosomes
http://www.nature.com/scitable/topicpage/karyotyping-for-chromosomal-abnormalities-298

5. Heterochromatin and genetic inactivation: Heterochromatin, the sex chromatin, correlation between the number of chromatin masses and the number of X chromosomes.
http://www.nature.com/scitable/topicpage/x-chromosome-x-inactivation-323

6. Chromosome mutations in Man Numerical and structural changes
and http://www.nature.com/scitable/topicpage/chromosomal-abnormalities-aneuploidies-290

UNIT-III
1. Human Genome Project: Introduction, History, Goals,
2. Benefits, Social, Ethical and Legal Issues
Human Genome Project

3. DNA Forensic Databases, Ethical, Legal, and Social Issues Associated with
DNA Databanking, Potential Benefits of DNA Databanking,
Forensics, DNA Fingerprinting, and CODIS
Government plans DNA database to help find missing people
Overview and Concerns Regarding the Indian Draft DNA Profiling Act 
 Forensic databases: benefits and ethical
and social costs
4. Human Genome Diversity Project: Introduction, History, Goals, Benefits
 Human Genome Diversity Project
5. Genetic Discrimination, Behavioral genetics, Genetics and Violence
Genetics of aggression

 Behavioural Genetics: Why Eugenic Selection is Preferable
to Enhancement

THE SCARLET GENE: BEHAVIORAL GENETICS, CRIMINAL LAW, AND RACIAL AND ETHNIC STIGMA

UNIT-IV
1. Introduction to conservation genetics

Conservation Genetics
Conservation Genetics 2
2. Species or subspecies? Resolving taxonomic uncertainty
SUBSPECIES, SEMI SPECIES, SUPER SPECIES
Species and Subspecies
 3. Wild populations, captive populations and conservation management unitsBottlenecks and Founder Efects 
 Estimating population structure
4. Genetics and Reproduction, Cloning, Genetic selection
Conservation Genetics 
5. Using molecular biology for species preservation
LaCONES
DNA barcoding

general forensic biology



     some links to useful videos for syllabus:

    Hematrace  Test

       6. Behavioral Genetics I

       7. Behavioral Genetics II

               3rd Semester practical IFSC
        Glucose-6-Phosphate Dehydrogenase Deficiency (G6PD Deficiency)


     Hb agarose gel Electrophoresis
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