MSc Semester 2 old2




UNIT-I

1 Chemistry of Nucleotides, Structure of DNA/RNA


https://en.wikibooks.org/wiki/Structural_Biochemistry/Organic_Chemistry/Nucleic_Acids_(DNA)

Original Watson Crick Paper
 https://www.nature.com/scitable/content/16331/molecularstructureofDNAswatsoncrick.pdf#toolbar=0&zoom=100

optional extra:
 commented Watson Crick Paper http://www.exploratorium.edu/origins/coldspring/printit.html
http://www.nature.com/scitable/topicpage/dna-replication-and-checkpoint-control-in-s-14202419

https://www.nature.com/scitable/topicpage/discovery-of-dna-structure-and-function-watson-397

http://www.rsc.org/Education/Teachers/Resources/cfb/nucleicacids.htm
2 DNA Replication: Eukaryotic and Prokaryotic Helicases, Topoisomerases and other DNA replicating Enzymes


http://www.nature.com/scitable/topicpage/major-molecular-events-of-dna-replication-413

https://www.dnalc.org/resources/3d/04-mechanism-of-replication-advanced.html


https://www.youtube.com/watch?v=I9ArIJWYZHI




3 DNA Denaturation, Cot-Rot curves,
http://faculty.tru.ca/dnelson/courses/biol335/335notes/3recdna/4-hybrization/recDNA3b.html


4 DNA Repair mechanisms
http://www.nature.com/scitable/topicpage/dna-damage-repair-mechanisms-for-maintaining-dna-344 
 
 http://www.youtube.com/watch?v=xS6bJMcOrAk

DNA repair - NHEJ - Canonical Non-homologus end joining pathway 2.0 - Full


http://www.youtube.com/watch?v=72oT6N90iWc

DNA repair : Base excision repair SHORT patch v

http://www.youtube.com/watch?v=9PEdqBuDMHM

Homologous Recombination of Double Strand Breaks

http://www.youtube.com/watch?v=g4khROaOO6c


DNA repair: Base excision repair LONG patch 1.0 -



http://www.youtube.com/watch?v=4CIWfTZVlfg

AP Biology - DNA Ligase and its Function


5 DNA Epigenetics
http://www.nature.com/scitable/topicpage/epigenetic-influences-and-disease-895
 

6 Eukaryotic and Prokaryotic Transcription.

http://www.nature.com/scitable/topicpage/dna-transcription-426RNA Processing and Editing


http://www.youtube.com/watch?v=WsofH466lqk


Transcription



http://www.youtube.com/watch?v=7ZpZ4fu7PAU


GENETICS2: TRANSCRIPTION TERMINATION

 http://www.youtube.com/watch?v=SMtWvDbfHLo

DNA Transcription (Advanced)

7 RNA Processing and Editing


http://www.youtube.com/watch?v=FVuAwBGw_pQ
mRNA Splicing

http://www.youtube.com/watch?v=YjWuVrzvZYA

mRNA Processing

https://www.youtube.com/watch?v=FVuAwBGw_pQ


RNA Splicing

(for other virtual cell animations visit http://vcell.ndsu.edu/animations/ )
8 Protein synthesis and Gene Regulation



 http://www.nature.com/scitable/topicpage/nucleic-acids-to-amino-acids-dna-specifies-935


http://www.youtube.com/watch?v=5bLEDd-PSTQ



Translation


http://www.youtube.com/watch?v=Ikq9AcBcohA

Protein Synthesis Animation Video



http://www.youtube.com/watch?v=TfYf_rPWUdY

mRNA Translation (Advanced)
optional extra: 
https://www.dnalc.org/

UNIT-II

1 Humoral and Cellular Immunology

 https://youtu.be/sYjtMP67vyk

 + power point presentations HUMORAL IMMUNOLOGY.pdf  + cellular responses.pdf

2 Structure and Functional Properties of Antibodies

 power point presentations ANTIBODIES.pdf

3 Production of Antibodies

 power point presentations ANTIBODIES.pdf


5 Complement System, Activation and Regulation

 https://youtu.be/d6qFPegEYV0

https://medlineplus.gov/lab-tests/c-reactive-protein-crp-test/

https://www.ncbi.nlm.nih.gov/books/NBK27100/

UNIT-III

1 Amino Acids, Proteins, Carbohydrates and Lipids: Structure and Functions

2 Metabolism of essential Amino Acids and Urea Cycle, Denovo and Salvage pathway for Nucleotide Synthesis

3 Bioenergetics, Glycolysis, Citric Acid Cycle, Oxidative Phosphorylation,

4 Oxidation of Fatty acids,

5 Gluconeogenesis

6 Hormonal Regulation

UNIT-IV

1 Introduction to Microbiolgy

2 Bacteria Structure and Function

3 Viruses and Prions

4 Eukaryotic pathogens

5 Fungi and Parasites

6 Microbial growth and Metabolism

7 Microbial genetics

8 Immunization, sterilization and disinfection

9 Fighting infections

10 Microbial Forensics: Applications in Bioterrorism, Building a national capacity to investigate Bioterrorism, Database for infectious microorganisms

11 Biocrimes, Microbial Forensics, and the Physician
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